Publications

Jason Li, Emily Rose, Daniel Frances, Yu Sun, Lidan You “Effect of oscillating fluid flow stimulation on osteocyte mRNA expression” Journal of Biomechanics (2012) Accepted

Saja Al-Dujaili, Chao Liu, Axel Guenther, Lidan You (2012) “Osteocytes exhibit multiple calcium oscillations in response to mechanical loading” ORS 58th Annual Meeting, February 4-7, 2012, San Francisco, California, USA.

Jia Ning Zhang, Chao Liu, Lidan You (2012) “The Effect of Mechanical Stimulation on Osteocyte Chemo-Sensitivity” ORS 58th Annual Meeting, February 4-7, 2012, San Francisco, California, USA.

Wing-Yee Cheung, Craig A. Simmons, Lidan You, “Osteocyte apoptosis regulates osteoclast precursor adhesion via osteocytic IL-6 secretion and endothelial ICAM-1 expression” Bone 50 (2012) 104–110

Saja A. Al-Dujaili, Esther Lau, Hashem Al-Dujaili, Kyle Tsang, Axel Guenther, Lidan You, “Apoptotic osteocytes regulate osteoclast precursor recruitment and differentiation in vitro“, Journal of Cellular Biochemistry 112:2412-2423 (2011)

Esther Lau, Whitaik David Lee, Jason Li, John E. Davies, Qianhong Wu, Liyun Wang, Lidan You, “Effect of low-magnitude, high-frequency vibration on osteogenic differentiation of rat mesenchymal stromal cells”, Journal of Orthopedic Research, 2011 Feb 22

Wing-Yee Cheung, Chao Liu, Rachel Tonelli Zasarsky, Craig A. Simmons, Lidan You, “Osteocyte Apoptosis is Mechanically Regulated and Induces Angiogenesis In Vitro”, Journal of Orthopedic Research, 2011 April ;29(4):523-30

Esther Lau, Saja Al-Dujaili, Axel Guenther, Dawei Liu, Liyun Wang, Lidan You “Effect of low-magnitude, high-frequency vibration on osteocytes in the regulation of osteoclasts” Bone. Volume 46, Issue 6, June 2010, Pages 1508-1515 (Top 8 in downloads from Bone from April to June, 2010)

Chao Liu, Yan Zhao, Wing-Yee Cheung, Ronak Gandhi, Liyun Wang, Lidan You “Effects of cyclic hydraulic pressure on osteocytes” Bone. Volume 46, Issue 5, May 2010, Pages 1449-1456

Jan-Hung Chen, Chao Liu, Lidan You, Craig A. Simmons “Boning up on Wolff’s Law: Mechanical regulation of the cells that make and maintain bone” Journal of Biomechanics 43 (2010) 108-118 (Top 10 in downloads from J. of Biomech from Jan. to Mar. 2010)

Saja Al-Dujaili, Kyle Tsang, Lidan You (2010) “Apoptotic Osteocytes Directly and Indirectly Promote Osteoclast Formation” ORS 56th Annual Meeting, March 6-9, 2010 in New Orleans, Louisiana.Emily Rose, Lidan You (2010) “Osteocytes differentially respond to different levels of shear stress” ORS 56th Annual Meeting, March 6-9, 2010 in New Orleans, Louisiana.

Esther Lau, Hong Lu, Dawei Liu, Lidan You (2010) “Low-magnitude, high-frequency vibration inhibits osteoclast formation via soluble factors from MLO-Y4 osteocytes” ORS 56th Annual Meeting, March 6-9, 2010 in New Orleans, Louisiana.(oral)

Esther Lau, Lidan You (2010) “Effect of low-magnitude, high-frequency vibration on the osteogenic differentiation of bone marrow stromal cells” ORS 56th Annual Meeting, March 6-9, 2010 in New Orleans, Louisiana.

Chao Liu, Ronak Gandhi, Liyun Wang, Lidan You (2010) “Effect of Cyclic Hydraulic Pressure on Osteocytes” ORS 56th Annual Meeting, March 6-9, 2010 in New Orleans, Louisiana.

Wing-Yee Chueng, Craig Simmons, Lidan You (2010) “TNF-alfa Induced Osteocyte Apoptosis Promotes Tubule Network Formation In Vitro Possibly Via VEGF” ORS 56th Annual Meeting, March 6-9, 2010 in New Orleans, Louisiana. (oral)

Hui Lu, Esther Lau, Andrew Xiao, Lidan You, and Dawei Liu (2010) “Biological Responses of Cementoblasts to Mechanical Vibration in Vitro” American Association for Dental Research Annual Meeting, March 3-6, 2010, Washington, DC US

Zhe Lu, Christopher Moraes, Yan Zhao, Lidan You, Craig A. Simmons, and Yu Sun (2010) “A Micromanipulation System for Single Cell Deposition” IEEE Conf. Robotics and Automation, Anchorage, Alaska, USA. May 3 – 8, 2010. (847 selected from 2062 submissions)

Al-Dujaili, S., Guenther, A., You, L. “Microfluidic Co-Culture System for Studying the Effect of Mechanical Loading on Osteocyte-Mediated Bone Remodeling” (2009) Orthopaedic Research Society 55th Annual Meeting

Cheung, W., Liu, C., Simmons, C. A., You, L. “Osteocyte Apoptosis is Flow-Regulated and Promotes Endothelial Cell Proliferation and Migration” (2009) Orthopaedic Research Society 55th Annual Meeting

Han, E. S., Yu, X., Zhao, Y., Bolz, S., Lidington, D., Heximer, S., Simmons, C. A., You, L. “The Role of the Sphingosine-1-Phosphate Signaling Pathway in Osteocyte Mechanotransduction” (2009) Orthopaedic Research Society 55th Annual Meeting

Lau, E., Pang, Q., You, L. “Cellular and molecular mechanism underlying the anti-resorptive effect of low-magnitude, high-frequency vibrations on bone” (2009) Orthopaedic Research Society 55th Annual Meeting

Zhao, Y., Leung, L., You, L. “Biodegradable One-Layer Micro Flow Chamber-Channel Structure: New Perspective for Bone Tissue Engineering” (2009) Orthopaedic Research Society 55th Annual Meeting

Lidan You, Sara Temiyasathit, Sean R. Coyer, Andreas J. Garcia, Christopher R. Jacobs “Bone Cells Grown on Micropatterned Surfaces are More Sensitive to Fluid Shear Stress”, Cellular and Molecular Bioengineering. 1(2-3): 182-188, 2008.

Lidan You, Eric Tao, Fritz Prinz, and Christopher R. Jacobs “3D Microfluidic Approach to Mechanical Stimulation of Osteocyte Processes”, Cellular and Molecular Bioengineering, 1(1): 103-107, 2008.

You, L., Temiyasathit, S., Lee, P., Kim, C.H., Tummala, P., Yao, W., Kingery, W., (…), Jacobs, C.R. Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading (2008) Bone, 42 (1), pp. 172-179.

Malone, A.M.D., Batra, N.N., Shivaram, G., Kwon, R.Y., You, L., Kim, C.H., Rodriguez, J., (…), Jacobs, C.R. The role of actin cytoskeleton in oscillatory fluid flow-induced signaling in MC3T3-E1 osteoblasts (2007) American Journal of Physiology – Cell Physiology, 292 (5), pp. C1830-C1836.

Kim, C.H., You, L., Yellowley, C.E., Jacobs, C.R. Oscillatory fluid flow-induced shear stress decreases osteoclastogenesis through RANKL and OPG signaling (2006) Bone, 39 (5), pp. 1043-1047.

Nikhil N. Batra, Ying J. Li, Clare E. Yellowley, Lidan You, Amada Malone, Chi Hyun Kim, Christopher R. Jacobs (2005) Effects of short term recovery periods on fluid induced signaling in osteoblastic cells Journal of Biomechanics. 38: 1909-1917.

Ying J. Li, Nikhil N. Batra, Lidan You, Stephen C. Meier, Ian A. Coe, Clare E. Yellowley, Christopher R. Jacobs (2004) Oscillatory fluid flow affects human marrow stromal cell proliferation and differentiation. Journal of Orthopaedic Research 22: 1283-1289.

Lidan You, Sheldon Weinbaum, Stephen C. Cowin, Mitchell B. Schaffler (2004) Ultrastructure of the osteocytes process. Anatomical Record 278A(2): 505-513.

Sheldon Weinbaum, Peng Guo, and Lidan You (2001) A new view of mechanotransduction and strain amplification in cells with microvilli and cell processes. Biorheology 38: 119-142.

You, L., Cowin, S.C., Schaffler, M.B., Weinbaum, S. A model for strain amplification in the actin cytoskeleton of osteocytes due to fluid drag on pericellular matrix (2001) Journal of Biomechanics, 34 (11), pp. 1375-1386.

Weinbaum, S., Guo, P., You, L. A new view of mechanotransduction and strain amplification in cells with microvilli and cell processes (2001) Biorheology, 38 (2-3), pp. 119-142.

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