The Cellular Biomechanics Laboratory at the University of Toronto was established in 2006. It is affiliated with both the Department of Mechanical and Industrial Engineering and the Institute of Biomaterials and Biomedical Engineering.

Our research interest is focused on solving biomechanical questions in muscular skeletal system at the cellular level. In specific, we are working on the anti-resorptive effect of mechanical loading on bone tissue; advanced microfluidics system for bone cell mechanotransduction study; the role of focal adhesion assembly in cell mechanosensitivity using micropatterned surface; development of advanced artificial bone matrix by employing novel microfabrication technologies; and the effect of mechanical loading on cancer metastasis in bone.

Our recent published work on microfluidic capture of multiple myeloma cells by Tony was featured by the British Society for Haemotology here and feature by Bioanalysis Zone here!

Our work was recently featured as editor’s choice on Science Translational Medicine! Read more about it here.

Check out the video below where Vivian Ma talks about her work for HubLE’s Thesis Report!

Check out the video below where Henry is interviewed about his publication on the OCY454 osteocytes!

Check out Amel’s video for TEXPO 2023 where she discusses our lab’s Bone Metastasis on a Chip Platform and some of the results we have uncovered thus far!

Open Positions!

There are openings for Master, PhD, and summer/thesis student.